Fibromyalgia and insomnia, disability associated with pain

In adults with fibromyalgia and insomnia, higher levels of perceived pain-related disability and increased difficulty falling asleep were associated with higher levels of anxiety, according to a study presented at the Associated Professional Sleep conference. Societies (SLEEP) 2022.

In adults with fibromyalgia and insomnia, higher levels of perceived pain-related disability and increased difficulty falling asleep were associated with higher levels of anxiety, according to the findings of a study presented at the conference.Professional sleep companies associated (SON) 2022.

Most patients with fibromyalgia report having poor or unresponsive sleep and do not feel rested when waking up compared to healthy controls. The effects of sleep disturbances on the severity of the symptoms of the disease (myalgia, tenderness and fatigue) are complex and multidimensional pathophysiological mechanisms. Patients with fibromyalgia with poor sleep quality show a higher degree of pain, a worse psychological state, more impaired bodily functions and a poorer quality of life than those with good sleep quality.

In fibromyalgia, up to 90% of patients suffer from comorbid sleep disorders (e.g., insomnia) and up to 64% suffer from comorbid anxiety disorders. Previous research has shown a two-way relationship between insomnia and anxiety, associations between pain and insomnia, and associations between pain and anxiety.

However, research still needs to improve understanding of the role of pain, especially pain-related disability, in moderating the association between insomnia and anxiety. The aim of the present study was to assess the moderating impact of self-reported pain-related disability on the relationship between subjective sleep variables and anxiety scores in adults with fibromyalgia and insomnia, the authors said.

Analysis of fibromyalgia and insomnia
The study included 219 adults with fibromyalgia I insomnia (Mage = 51.53, 92.8% women) who completed the fourteen-day sleep diaries, the Pain Disability Index (PDI), and the Y-1 State Trait Anxiety Inventory Form ( STAI-Y1) as part of the reference information provided for a larger randomized clinical trial (SPIN).

Moderation analyzes included STAI-Y1 as a dependent variable, that of to sleep average for 14 days (Sleep Onset Latency-SOL, Wake After Sleep Onset-WASO, Total Sleep Time-TST, Sleep Efficiency-% SE) as independent variables, PDI as moderator and age and years of education as covariates.

Relationship between pain, sleep and anxiety
The researchers found that higher levels of perceived pain-related disability and increased difficulty falling asleep were associated with higher levels of pain. anxiety higher in adults with fibromyalgia and insomnia. They observed that the relationship between difficulty falling asleep and anxiety levels can be reversed with lower levels of pain-related disability.

PDI moderated the relationship between SOL and STAI-Y1 (B = 0.0052, SE = 0.0019, p = 0.01, R2 = 0.04). At high (but not medium) PDI scores, a higher SOL was associated with higher STAI-Y1 scores (B = 0.0748, SE = 0.0310, p = 0.02). At low PDI scores, a higher SOL was associated with lower STAI-Y1 scores (B = −0.0844, SE = 0.0453, p = 0.06 for the trend).

“At lower levels of pain-related disability, difficulty falling asleep, and anxiety levels may have an inverse relationship,” the authors noted. “This points to a possible complex interaction between sleep difficulties, pain-related disabilities, and anxiety in this patient population. Therefore, more research is needed to study the possible causal relationships between pain, sleep, and anxiety.

Bibliography

Guandique A et al. 0650 Does Pain-Related Disability Moderate the Relationship Between Subjective Insomnia and Anxiety in Comorbid Fibromyalgia and Insomnia? Sleep, Volume 45, Supplement Issue_1, June 2022, page A286.

Laws

Leave a Comment